Wrinkle Treatments – Review of Popular Prescriptions

How Do Wrinkles on the Face Form?

Wrinkles are a by-product of our aging bodies.  Wrinkles are inevitable as we age.  Most wrinkles are generally found around the eyes, necks, and cheeks.  How do we define wrinkles? Wrinkles are fine lines or creases in the skin, primarily in the face, that usually result from a combination of factors, including sun and weather damage, smoking, and natural aging.Wrinkles cannot be prevented, according to the Mayo Clinic. However, they say that proper care of your skin can help delay and reduce wrinkles.  You may find it interesting that wrinkles can be hereditary, and some families are more prone to wrinkles than others.  According to the Mayo Clinic website information, Wrinkles are classified into three classes. 

Class   I: Fine wrinkles

Class  II: Fine-to-moderately deep wrinkles and moderate number of lines

Class III: Fine-to-deep wrinkles, numerous lines, and possibly redundant folds


There are an abundance of treatments marketed today, both for in-home use as well as in spas and clinics, which aim to be highly effective at treating skin.  Treatment for deep wrinkles tends to be a little more complex than that of fine, thinner lines, but wrinkle injection treatments, as well as laser and radio wave based procedures, are making any type of wrinkle removal increasingly manageable.  Treatment options include dermabrasion, chemical peels and laser skin resurfacing.  Treatment with the Erbium laser stimulates the production of collagen which results in a tightening and smoothing of the skin.  Despite great demand, most such products and treatments have not been proven to give lasting or major positive effects.  Besides its cosmetic application, Botox is used in the treatment of other conditions including migraine headache and cervical dystonia (spasmodic torticollis) (a neuromuscular disorder involving the head and neck).  Therefore, if you still want to reduce wrinkles, explore your treatment options.There are various creams and lotions to treat wrinkles available over-the-counter.  Prescription treatments, including the retinoid cream renova, are also an option.


Collagen is what supports the skin.  Elastin is what gives the skin its flexibility. Collagen and keratin leave a protein film and temporarily stretch the skin. Collagen is what keeps your skin tight and toned, so using collagen targeted products can help you fill in wrinkled areas of your face.   Collagen or hyaluronic acid (Restylane, Hyalaform, Captique, for example), may be injected under wrinkles or folds to elevate them.   Collagen Replacement Therapy is a wrinkle therapy that provides Collagen treatment on a localized basis in salons.


Botox injections have become very popular in recent years.  In fact, many ENT Doctors have re-invented their medical practices to market Botox and anti-aging medicine, supplements, and wrinkle products. Botox is another technique available to help minimize wrinkles.  According to the manufacturers of Botox, BOTOX® is a medicine made from a highly purified, naturally occurring protein which has the ability to very precisely relax the muscles to which it is applied.  BOTOX® does not affect the nerves responsible for sensation, so there is no numbness in the treated areas.  BOTOX® relaxes the muscles which cause many facial lines and unwanted facial expressions.  BOTOX Cosmetic(TM) is very affordable even for those with modest incomes, but some people need to budget for it just as they would for buying accessories like shoes and having their hair styled.  BOTOX® Cosmetic treatments provide a safe, quick and remarkably effective way to markedly decrease wrinkles.  BOTOX® Cosmetic injections are best on the upper third of the face.


Besides wrinkles, Restylane is supposed to also fight fine lines and folds.  According the the manufacturers of Restylane, the types of skin folds Restylane targets are “Nasolabial Folds,” or the ridges that some people have from the base of their nose to the corners of their mouth.  Restylane® is a wrinkle filler used to treat “laugh lines” (the lines between the nose and the corner of the mouth), vertical lip lines, and folds in the skin for both men and women.

Other Wrinkle Reduction Products

Retinol, a natural form of vitamin A, could not, until recently, be used in skin products because it was unstable and easily broken down by UV radiation.  The FDA warns that over-the-counter retinol skin products are unregulated; the amount of active ingredients is unknown, and some preparations, in fact, may contain almost no retinol.  Retin-A, Renova, Avita (drug name tretinoin) and Tazorac (drug name tazarotene), prescribed by your doctor or dermatologist, are still the gold standards among topical prescription products for improving the appearance of sun-damaged (wrinkled and discolored) skin.

Wrinkles in the face can unfortunately cause a person to appear older than they truly are, or simply reveal their true age.  If your wrinkles are bothering you, you have more options than ever to help eliminate or at least diminish their appearance.  By Dr. Robert Cox, Ph.D. 

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